Nanotechnology Project

Get the findNano iPhone application


Environment, Health and Safety Research

Dynamics, distribution and photochemistry of quantum dots in blood vessels

Project Information

Principal InvestigatorDavid Cramb
InstitutionUniversity of Calgary
Project URLView
Relevance to ImplicationsHigh
Class of NanomaterialEngineered Nanomaterials
Impact SectorHuman Health
Broad Research Categories Hazard
Generation, Dispersion, Transformation etc.
NNI identifier

Funding Information

Anticipated Total Funding$86,883.00
Annual Funding$43,441.50
Funding SourceNSERC
Funding MechanismExtramural
Funding SectorGovernment
Start Year2005
Anticipated End Year2007


There is significant need for data that will help us to predict the distribution of nanoparticles in the blood stream. We propose to develop a model system for blood vessels in which to examine the distribution and dynamics of quantum dot nanoparticles. We will determine the affect of quantum dot size and surface chemistry on their localization and transportation dynamics in the blood vessel system of a chick embryo’s chorioallantoic membrane (CAM). The CAM is a membrane that functions as a chicken embryos lungs during early development. The CAM has a blood vessel system that will be used as a test bed for quantum dot behavior in more complex living systems. We will create an information matrix that will allow the prediction of quantum behavior in the blood vessels of higher organisms.