Dynamics, distribution and photochemistry of quantum dots in blood vessels
|Principal Investigator||David Cramb|
|Institution||University of Calgary|
|Relevance to Implications||High|
|Class of Nanomaterial||Engineered Nanomaterials|
|Impact Sector||Human Health|
|Broad Research Categories||
Generation, Dispersion, Transformation etc.
|Anticipated Total Funding||$86,883.00|
|Anticipated End Year||2007|
There is significant need for data that will help us to predict the distribution of nanoparticles in the blood stream. We propose to develop a model system for blood vessels in which to examine the distribution and dynamics of quantum dot nanoparticles. We will determine the affect of quantum dot size and surface chemistry on their localization and transportation dynamics in the blood vessel system of a chick embryo’s chorioallantoic membrane (CAM). The CAM is a membrane that functions as a chicken embryos lungs during early development. The CAM has a blood vessel system that will be used as a test bed for quantum dot behavior in more complex living systems. We will create an information matrix that will allow the prediction of quantum behavior in the blood vessels of higher organisms.