Nanotechnology Project

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Environment, Health and Safety Research

Nanoparticles in Phospholipid Membrane Environments

Project Information

Principal InvestigatorBruce Lennox
InstitutionMcGill University
Project URLView
Relevance to ImplicationsHigh
Class of NanomaterialEngineered Nanomaterials
Impact SectorHuman Health
Broad Research Categories Characterization
NNI identifier

Funding Information

Anticipated Total Funding$86,883.00
Annual Funding$43,441.50
Funding SourceNSERC
Funding MechanismExtramural
Funding SectorGovernment
Start Year2005
Anticipated End Year2007


Metal and semiconductor nanoparticles are certain to be a major player in the world of nanomaterials. Their remarkable optical, electronic, and physical properties are already finding use in devices and biosensors. These nanoparticles can be used in important applications because they are stabilized with small molecules (ligands) which form a protective layer on the 1-15nm particles. Without this protective layer the particles will aggregate and revert to the bulk material state. This proposal is directed toward a detailed assessment of the mechanism by which these ligands can be released by the nanoparticles and replaced with another ligand or ion. This is important because the released ligands tend to be chemically reactive and may participate in undesired secondary reactions. Understanding the mechanism of ligand release will allow for a rational design of new ligands with a lesser rate or extent of release.