Nanotechnology Project

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Environment, Health and Safety Research

Pulmonary Effects of Exposure to Various Nanoparticles

Project Information

Principal InvestigatorDale Porter
InstitutionNational Institute for Occupational Safety and Health
Project URLView
Relevance to ImplicationsHigh
Class of NanomaterialEngineered Nanomaterials
Impact SectorHuman Health
Broad Research Categories Exposure
NNI identifier

Funding Information

Anticipated Total Fundingn/a
Annual Fundingn/a
Funding SourceNIOSH
Funding MechanismIntramural
Funding SectorGovernment
Start Year2005
Anticipated End Year2008


The purpose of this project is to evaluate several types of nanoparticles for toxicity in the conducting airways and alveolar region of the lung, and to understand their mechanisms of toxicity by comparing the effects of pulmonary exposure to fine versus ultrafine metal oxide particles. The data obtained will contribute to the development of a toxicological database necessary for hazard identification and to the NIOSH Nanotechnology and Health and Safety Research Program. The project will provide data to NIOSH, OSHA, and EPA for nanoparticle exposure risk assessment and prevention.